Human plasma PeptideAtlas

被引:111
作者
Deutsch, EW
Eng, JK
Zhang, H
King, NL
Nesvizhskii, AI
Lin, BY
Lee, HK
Yi, EC
Ossola, R
Aebersold, R
机构
[1] Inst Syst Biol, Seattle, WA 98103 USA
[2] ETH, Inst Mol Syst Biol, Zurich, Switzerland
[3] Univ Zurich, Fac Nat Sci, Zurich, Switzerland
关键词
databases; human; Human Proteome Organisation; plasma proteome; tandem mass spectrometry;
D O I
10.1002/pmic.200500160
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Peptide identifications of high probability from 28 LC-MS/MS human serum and plasma Received: March 16,2005 experiments from eight different laboratories, carried out in the context of the HUPO Plasma Accepted: March 31, 2005 Proteome Project, were combined and mapped to the EnsEMBL human genome. The 6929 distinct observed peptides were mapped to approximately 960different proteins. The resulting compendium of peptides and their associated samples, proteins, and genes is made publicly available as a reference for future research on human plasma.
引用
收藏
页码:3497 / 3500
页数:4
相关论文
共 15 条
  • [1] Toward a human blood serum proteome - Analysis by multidimensional separation coupled with mass spectrometry
    Adkins, JN
    Varnum, SM
    Auberry, KJ
    Moore, RJ
    Angell, NH
    Smith, RD
    Springer, DL
    Pounds, JG
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2002, 1 (12) : 947 - 955
  • [2] The human plasma proteome - History, character, and diagnostic prospects
    Anderson, NL
    Anderson, NG
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2002, 1 (11) : 845 - 867
  • [3] The human plasma proteome - A nonredundant list developed by combination of four separate sources
    Anderson, NL
    Polanski, M
    Pieper, R
    Gatlin, T
    Tirumalai, RS
    Conrads, TP
    Veenstra, TD
    Adkins, JN
    Pounds, JG
    Fagan, R
    Lobley, A
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2004, 3 (04) : 311 - 326
  • [4] Chan K. C., 2004, CLIN PROTEOM, V1, P101, DOI DOI 10.1385/CP:1:2:101
  • [5] Desiere F, 2005, GENOME BIOL, V6
  • [6] AN APPROACH TO CORRELATE TANDEM MASS-SPECTRAL DATA OF PEPTIDES WITH AMINO-ACID-SEQUENCES IN A PROTEIN DATABASE
    ENG, JK
    MCCORMACK, AL
    YATES, JR
    [J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1994, 5 (11) : 976 - 989
  • [7] Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
    Keller, A
    Nesvizhskii, AI
    Kolker, E
    Aebersold, R
    [J]. ANALYTICAL CHEMISTRY, 2002, 74 (20) : 5383 - 5392
  • [8] The International Protein Index: An integrated database for proteomics experiments
    Kersey, PJ
    Duarte, J
    Williams, A
    Karavidopoulou, Y
    Birney, E
    Apweiler, R
    [J]. PROTEOMICS, 2004, 4 (07) : 1985 - 1988
  • [9] Advancement of biomarker discovery and validation through the HUPO plasma proteome project
    Omenn, GS
    [J]. DISEASE MARKERS, 2004, 20 (03) : 131 - 134
  • [10] The Human Proteome Organization Plasma Proteome Project pilot phase: Reference specimens, technology platform comparisons, and standardized data submissions and analyses
    Omenn, GS
    [J]. PROTEOMICS, 2004, 4 (05) : 1235 - 1240