Biomarkers of inflammatory bowel disease activity

被引:4
作者
Fadeeva, N. A. [1 ]
Korneeva, I. A. [1 ]
Knyazev, O. V. [1 ]
Parfenov, A. I. [1 ]
机构
[1] Dept Hlth Moscow, AS Loginov Moscow Clin Res & Pract Ctr, Moscow, Russia
关键词
Crohn's disease; inflammatory bowel disease; C calgranulin; M-2 pyruvate kinase; irritable bowel syndrome; fecal calprotectin; ulcerative colitis; C-REACTIVE PROTEIN; FECAL CALPROTECTIN CONCENTRATION; ULCERATIVE-COLITIS; INTRAINDIVIDUAL VARIABILITY; ENDOSCOPIC ACTIVITY; LACTOFERRIN; MARKERS; RECURRENCE; DIAGNOSIS; UTILITY;
D O I
10.26442/00403660.2018.12.000018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The review presents data on calprotectin, lactoferrin, leukocytes labeled with isotope indium In-111, calgranulin C and pyruvate kinase type M-2 - highly sensitive biomarkers to assess the severity of intestinal inflammation. Their importance in diagnostics, determination of treatment efficiency, including as predictors of recurrence of ulcerative colitis and Crohn's disease is shown.
引用
收藏
页码:107 / 111
页数:5
相关论文
共 30 条
[1]   Fecal Markers: Calprotectin and Lactoferrin [J].
Abraham, Bincy P. ;
Kane, Sunanda .
GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2012, 41 (02) :483-+
[2]   Adalimumab in prevention of postoperative recurrence of Crohn's disease in high-risk patients [J].
Aguas, Mariam ;
Bastida, Guillermo ;
Cerrillo, Elena ;
Beltran, Belen ;
Iborra, Marisa ;
Sanchez-Montes, Cristina ;
Munoz, Fernando ;
Barrio, Jesus ;
Riestra, Sabino ;
Nos, Pilar .
WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (32) :4391-4398
[3]   Levels of Fecal Calprotectin Are Associated With the Severity of Postoperative Endoscopic Recurrence in Asymptomatic Patients With Crohn's Disease [J].
Boschetti, Gilles ;
Laidet, Marc'harid ;
Moussata, Driffa ;
Stefanescu, Carmen ;
Roblin, Xavier ;
Phelip, Gildas ;
Cotte, Eddy ;
Passot, Guillaume ;
Francois, Yves ;
Drai, Jocelyne ;
del Tedesco, Emilie ;
Bouhnik, Yoram ;
Flourie, Bernard ;
Nancey, Stephane .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2015, 110 (06) :865-872
[4]   Inflammatory Bowel Disease in Pediatric Patients [J].
Buderus, Stephan ;
Scholz, Dietmar ;
Behrens, Rolf ;
Classen, Martin ;
De Laffolie, Jan ;
Keller, Klaus-Michael ;
Zimmer, Klaus-Peter ;
Koletzko, Sibylle .
DEUTSCHES ARZTEBLATT INTERNATIONAL, 2015, 112 (08) :121-127
[5]   Fecal Calprotectin and the Clinical Activity Index Are Both Useful to Monitor Medical Treatment in Patients with Ulcerative Colitis [J].
Burri, Emanuel ;
Beglinger, Christoph ;
von Felten, Stefanie ;
Lehmann, Frank Serge .
DIGESTIVE DISEASES AND SCIENCES, 2015, 60 (02) :485-491
[6]   High Within-day Variability of Fecal Calprotectin Levels in Patients with Active Ulcerative Colitis: What Is the Best Timing for Stool Sampling? [J].
Calafat, Margalida ;
Cabre, Eduard ;
Manosa, Miriam ;
Lobaton, Triana ;
Marin, Laura ;
Domenech, Eugeni .
INFLAMMATORY BOWEL DISEASES, 2015, 21 (05) :1072-1076
[7]   Faecal calprotectin: comparative study of the Quantum Blue rapid test and an established ELISA method [J].
Coorevits, Liselotte ;
Baert, Filip J. ;
Vanpoucke, Hilde J. M. .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2013, 51 (04) :825-831
[8]   Challenges to the Design, Execution, and Analysis of Randomized Controlled Trials for Inflammatory Bowel Disease [J].
D'Haens, Geert ;
Feagan, Brian ;
Colombel, Jean-Frederic ;
Sandborn, William J. ;
Reinisch, Walter ;
Rutgeerts, Paul ;
Carbonnel, Frank ;
Mary, Jean-Yves ;
Danese, Silvio ;
Fedorak, Richard N. ;
Hanauer, Steven ;
Lemann, Marc .
GASTROENTEROLOGY, 2012, 143 (06) :1461-1469
[9]   Consecutive Fecal Calprotectin Measurements to Predict Relapse in Patients with Ulcerative Colitis Receiving Infliximab Maintenance Therapy [J].
De Vos, Martine ;
Louis, Edouard J. ;
Jahnsen, Jorgen ;
Vandervoort, Jo G. P. ;
Noman, Maja ;
Dewit, Olivier ;
D'Haens, Geert R. ;
Franchimont, Denis ;
Baert, Filip J. ;
Torp, Roald A. ;
Henriksen, Magne ;
Potvin, Philippe M. R. ;
Van Hootegem, Philippe P. ;
Hindryckx, Pieter M. ;
Moreels, Tom G. ;
Collard, Arnaud ;
Karlsen, Lars Normann ;
Kittang, Eirik ;
Lambrecht, Guy ;
Grimstad, Tore ;
Koch, Jonas ;
Lygren, Idar ;
Coche, Jean-Claude R. J. ;
Mana, Fazia ;
Van Gossum, Andre ;
Belaiche, Jacques ;
Cool, Mike R. ;
Fontaine, Fernand ;
Maisin, Jean-Marc G. ;
Muls, Vinciane ;
Neuville, Bart ;
Staessen, Dirk A. J. ;
Van Assche, Gert A. ;
de Lange, Thomas ;
Solberg, Inger Camilla ;
Vander Cruyssen, Bert J. K. ;
Vermeire, Severine A. R. A. .
INFLAMMATORY BOWEL DISEASES, 2013, 19 (10) :2111-2117
[10]   Clinical importance of faecal calprotectin variability in inflammatory bowel disease: intra-individual variability and standardisation of sampling procedure [J].
Kristensen, Vendel ;
Malmstrom, Gunn Helen ;
Skar, Viggo ;
Roseth, Arne ;
Moum, Bjorn .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2016, 51 (05) :548-555