RNA turnover: Unexpected consequences of being tailed

被引:38
作者
Anderson, JT [1 ]
机构
[1] Marquette Univ, Dept Biol Sci, Milwaukee, WI 53201 USA
关键词
D O I
10.1016/j.cub.2005.08.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In eukaryotic cells, the Tpoly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3'end poly(A) tails in the nuclear surveillance and turnover of noncoding RNAs and intergenic mRNAs of unknown function.
引用
收藏
页码:R635 / R638
页数:4
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