Electrophysiological effects of angiotensin II. Part I: signal transduction and basic electrophysiological mechanisms

被引:47
作者
Goette, Andreas [1 ]
Lendeckel, Uwe [2 ]
机构
[1] Univ Hosp Magdeburg, Div Cardiol, D-39120 Magdeburg, Germany
[2] Univ Hosp Magdeburg, Inst Expt Internal Med, D-39120 Magdeburg, Germany
来源
EUROPACE | 2008年 / 10卷 / 02期
关键词
angiotensin; arrhythmias; fibrillation; molecular biology; receptors; signal transduction;
D O I
10.1093/europace/eum283
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In the recent years, a tremendous amount has been learned about the pathophysiology and molecular biology of the cardiac angiotensin 11 system. Interestingly, the angiotensin 11 appears to have several effects on cardiac electrophysiology, which have not been fully appreciated so far. Therefore, this review will highlight on the basic knowledge of signal transduction and electrophysiological effects of angiotensin 11, which may have an impact on the occurrence of cardiac arrhythmia.
引用
收藏
页码:238 / 241
页数:4
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