Yojironins A-D, meroterpenoids and prenylated acylphloroglucinols from Hypericum yojiroanum

被引：32

作者：

Mamemura, Takuji ^{[1
]}

Tanaka, Naonobu ^{[1
]}

Shibazaki, Azusa ^{[2
]}

Gonoi, Tohru ^{[2
]}

Kobayashi, Jun'ichi ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Chiba Univ, Med Mycol Res Ctr, Chiba 2600856, Japan

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 28期

关键词：

Hypericum yojiroanum; Meroterpenoids; Prenylated acylphloroglucinols; Yojironins A-D; PSEUDOPETIOLATUM VAR. KIUSIANUM; SPIRO-LACTONES; BIYOUYANAGIN-A; HYPERFORIN; BIOSYNTHESIS; PERFORATUM; CHINENSE; CULTURES;

D O I：

10.1016/j.tetlet.2011.04.106

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new meroterpenoids, yojironins A (1) and B (2), were isolated from the whole plants of Hypericum yojiroanum, together with two new prenylated acylphloroglucinols, yojironins C (3) and D (4). Their structures were elucidated by spectroscopic data. Yojironins A (1) and B (2) are biogenetically unique meroterpenoids, which seem to be composed of two acetate units with a 2-methylbutanoyl group and three isoprene units. Yojironin A (1) exhibited antimicrobial activity. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：3575 / 3578

页数：4

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