Larvicidal activity of tectoquinone isolated from red heartwood-type Cryptomeria japonica against two mosquito species

被引：79

作者：

Cheng, Sen-Sung ^{[1
]}

Huang, Chin-Gi ^{[2
]}

Chen, Wei-June ^{[3
]}

Kuo, Yueh-Hsiung ^{[4
]}

Chang, Shang-Tzen ^{[5
]}

机构：

[1] Natl Taiwan Univ, Nan Tou 557, Taiwan

[2] Natl Taiwan Univ, Dept Entomol, Taipei 106, Taiwan

[3] Chang Gung Univ, Dept Publ Hlth & Parasitol, Tao Yuan 33332, Taiwan

[4] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan

[5] Natl Taiwan Univ, Sch Forestry & Resource Conservat, Taipei 106, Taiwan

来源：

BIORESOURCE TECHNOLOGY | 2008年 / 99卷 / 09期

关键词：

Criptomeria Japonica; Aedes aegypti; Aedes albopictus; tectoquinone; mosquito larvicidal activity;

D O I：

10.1016/j.biortech.2007.07.038

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

Mosquito larvicidal activities of methanolic extracts from different plant parts of red heartwood-type Cryptomeria japonica D. Don against the fourth-instar larvae of Aedes acgypti and Aedes albopictus were examined. Results of mosquito larvicidal tests demonstrated that the n-hexane fraction of C. japonica sapwood methanolic extract had an excellent inhibitory effect against the larvae of A. aegypti and A. albopictus and its LC50 values were 2.4 and 3.3 mu g/ml, respectively, in 24 h. Following the bioactivity-guided fractionation procedure, the active constituent isolated from C. japonica sapwood was characterized as tectoquinone by spectroscopic analyses. The LC50 values of tectoquinone against A. aegypti and A. albopictus in 24 h were 3.3 and 5.4 mu g/ml, respectively. In addition, comparisons of mosquito larvicidal activity of anthraquinone congeners demonstrated that anthraquinone skeleton with a methyl group at C-2 position, such as tectoquinone, exhibited the strongest mosquito larvicidal activity. Results of this study show that the methanolic extract of C. japonica sapwood may be considered as a potent source and tectoquinone as a new natural mosquito larvicidal agent. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：3617 / 3622

页数：6

共 32 条

[11] Chemical composition and antifungal activity of essential oils from different tissues of Japanese cedar (Cryptomeria japonica) [J].