Antibacterial Properties of Sol-Gel Biomaterials with Different Percentages of PEG or PCL

被引：15
作者：
Catauro, Michelina [1 ]
Tranquillo, Elisabetta [1 ]
Dal Poggetto, Giovanni [2 ]
Naviglio, Silvio [3 ]
Barrino, Federico [1 ]
机构：
[1] Univ Campania Luigi Vanvitelli, Dept Engn, Via Roma 29, I-81031 Aversa, Italy
[2] Ecoricerche Srl, Via Principi Normanni 36, I-81043 Capua, Caserta, Italy
[3] Univ Campania Luigi Vanvitelli, Dept Precis Med, Via L De Crecchio 7, I-80138 Naples, Italy
来源：
MACROMOLECULAR SYMPOSIA | 2020年 / 389卷 / 01期
关键词：
antibacterial properties; chlorogenic acid; polymers; silica matrix; sol-gel method; CHLOROGENIC ACID; DELIVERY; HYBRIDS;
D O I：
10.1002/masy.201900056
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The aim of this work is the synthesis of antibacterial biomedical implants using sol-gel method. Different percentages (6, 12, 24, 50 wt%) of polyethylene glycol (PEG) or poly(epsilon-caprolactone) (PCL) are embedded in the silica matrix; subsequently, high amounts of chlorogenic acid (CGA 20 wt%) are added to SiO2/PEG and SiO2/PCL sol. Fourier transform infrared spectroscopy is used to evaluate the interactions among different organic and inorganic phases in the hybrid materials. Furthermore, in order to study the potential antibacterial properties of the materials, two different bacterial strains are used and the diameter of zone of inhibition is observed. CGA is a natural product that is present in coffee beans, as well as tea leaves, grapes, and apples. This natural molecule is added to sol-gel materials due to its many health-promoting properties.
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页数：3
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