Carbon disulfide reagent allows the characterization of nonpolar analytes by atmospheric pressure chemical ionization mass spectrometry

被引：32

作者：

Owen, Benjamin C. ^{[1
]}

Gao, Jinshan ^{[1
]}

Borton, David J., II ^{[1
]}

Amundson, Lucas M. ^{[1
]}

Archibold, Enada F. ^{[1
]}

Tan, Xiaoli ^{[3
]}

Azyat, Khalid ^{[2
]}

Tykwinski, Rik ^{[2
]}

Gray, Murray ^{[3
]}

Kenttaemaa, Hilkka I. ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

[2] Univ Alberta, Dept Chem, Edmonton, AB, Canada

[3] Univ Alberta, Dept Chem & Mat Engn, Edmonton, AB, Canada

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2011年 / 25卷 / 14期

关键词：

HYDROCARBONS; ELECTROSPRAY;

D O I：

10.1002/rcm.5063

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

While atmospheric pressure ionization methodologies have revolutionized the mass spectrometric analysis of nonvolatile analytes, limitations native to the chemistry of these methodologies hinder or entirely inhibit the analysis of certain analytes, specifically, many nonpolar compounds. Examination of various analytes, including asphaltene and lignin model compounds as well as saturated hydrocarbons, demonstrates that atmospheric pressure chemical ionization (APCI) using CS(2) as the reagent produces an abundant and stable molecular ion (M(+center dot)) for all model compounds studied, with the exception of completely saturated aliphatic hydrocarbons and the two amino acids tested, arginine and phenylalanine. This reagent substantially broadens the applicability of mass spectrometry to nonvolatile nonpolar analytes and also facilitates the examination of radical cation chemistry by mass spectrometry. Copyright (C) 2011 John Wiley & Sons, Ltd.

引用

页码：1924 / 1928

页数：5

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