Activation of the P-H bond by a frustrated Lewis pair and its application in catalytic Z-selective hydrophosphonylation of terminal ynones

被引：11

作者：

Liu, Yizhen ^{[1
]}

Fan, Xiaoting ^{[1
]}

Li, Zhen Hua ^{[1
]}

Wang, Huadong ^{[1
]}

机构：

[1] Fudan Univ, Dept Shanghai Key Lab Mol Catalysis & Innovat Mat, Dept Chem, Shanghai 200433, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 79期

基金：

中国国家自然科学基金;

关键词：

ACID/BRONSTED BASE CATALYSTS; FREE HYDROGEN ACTIVATION; CHEMISTRY; ACID;

D O I：

10.1039/c7cc05028c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The frustrated Lewis pair (FLP) comprised of B(C6F5)(3) and 1,2,2,6,6-pentamethylpiperidine (PMP) can efficiently catalyze Z-selective hydrophosphonylation of terminal ynones with a Z/E selectivity of up to 20 :1. Mechanistic studies suggest that the trans arrangement of the phosphite nucleophilic attack and hydrogen bond formation on the alkyne moiety is responsible for the observed Z-selectivity.

引用

页码：10890 / 10893

页数：4

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