An efficient synthesis of propargylamines using a silica gel anchored copper chloride catalyst in an aqueous medium

被引：70

作者：

Sreedhar, B. ^{[1
]}

Reddy, P. Surendra ^{[1
]}

Krishna, C. S. Vamsi ^{[1
]}

Babu, P. Vijaya ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Inorgan & Phys Chem Div, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 44期

关键词：

propargylamines; silica gel anchored copper chloride; mesoporous silica; terminal alkynes and imines;

D O I：

10.1016/j.tetlet.2007.08.116

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The design and development of a silica gel anchored copper chloride heterogeneous catalyst for the synthesis of propargylamines using an amine, an aldehyde, and an alkyne through C-H activation in water is described. Both aliphatic and aromatic aldehydes and amines are used for the reaction. The catalyst was recovered quantitatively by simple filtration and reused several times. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：7882 / 7886

页数：5

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