Determination of T-2 and HT-2 Toxins in Traditional Chinese Medicine Marketed in China by LC-ELSD after Sample Clean-Up by Two Solid-Phase Extractions

被引：17

作者：

Tan, Yinfeng ^{[2
]}

Kuang, Ying ^{[1
]}

Zhao, Runhuai ^{[3
]}

Chen, Bo ^{[3
]}

Wu, Jianwei ^{[1
,3
]}

机构：

[1] Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100193, Peoples R China

[2] Hainan Med Coll, Hainan Prov Key Lab R&D Trop Herbs, Hainan 571101, Peoples R China

[3] China Natl Grp Corp Tradit & Herbal Med, Technol Dev Ctr, Beijing 102600, Peoples R China

来源：

CHROMATOGRAPHIA | 2011年 / 73卷 / 3-4期

关键词：

Column liquid chromatography; LC-ESI-MS-MS; T-2; toxin; HT-2; Traditional chinese medicine; Functional food; CHROMATOGRAPHY-MASS-SPECTROMETRY; LIQUID-CHROMATOGRAPHY; TRICHOTHECENE MYCOTOXINS; GAS-CHROMATOGRAPHY; FLUORESCENCE DETECTION; CEREAL-GRAINS;

D O I：

10.1007/s10337-010-1890-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

LC-ELSD has been applied for the determination of T-2 and HT-2 toxins in Traditional Chinese Medicine (TCM) marketed in China. For sample preparation, two clean-up procedures were developed using Florisil and MycoSep227 for solid-phase extraction. Limits of detection (10 ng g(-1)) as well as recoveries are described. A total of 138 samples of 46 commercially available TCM samples was analyzed; only one sample was determined to contain T-2 at a level of 64.0 ng g(-1), and positive results were further confirmed by LC-ESI-MS-MS.

引用

页码：407 / 410

页数：4

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