Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp. .2. Structure determination

被引：32

作者：

Roggo, BE ^{[1
]}

Hug, P ^{[1
]}

Moss, S ^{[1
]}

Stampfli, A ^{[1
]}

Kriemler, HP ^{[1
]}

Peter, HH ^{[1
]}

机构：

[1] CIBA GEIGY AG,DEPT PHYS,RES SERV,CH-4002 BASEL,SWITZERLAND

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 04期

关键词：

D O I：

10.7164/antibiotics.49.374

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structures of six novel spirodihydrobenzofuranlactams I similar to VI (1 similar to 6) were determined by spectroscopic methods.

引用

页码：374 / 379

页数：6

共 6 条

[1]

GIOCOBBE RA, 1991, Patent No. 4981980

[2] STRUCTURE OF K-76, A COMPLEMENT INHIBITOR PRODUCED BY STACHYBOTRYS-COMPLEMENTI NOV-SP K-76 [J].

KAISE, H ;

SHINOHARA, M ;

MIYAZAKI, W ;

IZAWA, T ;

NAKANO, Y ;

SUGAWARA, M ;

SUGIURA, K .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1979, (16) :726-727

[3]

Kalinowski H.-O., 1984, 13C NMR SPEKTROSKOPI, P208

[4]

KALINOWSKI HO, 1984, 13C NMR SPEKTROSKOPI, P209

[5] MER-NF5003B, MER-NF5003E AND MER-NF5003F, NOVEL SESQUITERPENOIDS AS AVIAN-MYELOBLASTOSIS VIRUS PROTEASE INHIBITORS PRODUCED BY STACHYBOTRYS SP [J].

KANETO, R ;

DOBASHI, K ;

KOJIMA, I ;

SAKAI, K ;

SHIBAMOTO, N ;

YOSHIOKA, T ;

NISHIDA, H ;

OKAMOTO, R ;

AKAGAWA, H ;

MIZUNO, S .

JOURNAL OF ANTIBIOTICS, 1994, 47 (06) :727-730

[6] Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp .1. Fermentation, isolation and biological activity [J].

Roggo, BE ;

Petersen, F ;

Sills, M ;

Roesel, JL ;

Moerker, T ;

Peter, HH .

JOURNAL OF ANTIBIOTICS, 1996, 49 (01) :13-19

← 1 →