Palladium-Catalyzed N-Arylation of 3-Functionalized 2-Amino-4,5-dimethylpyrroles

被引：2
作者：
Griswold, Carlos P. [1 ]
Suthiwangcharoen, Nisaraporn [1 ]
Pochini, Steven M. [1 ]
Stephens, Chad E. [1 ]
机构：
[1] Augusta State Univ, Dept Chem & Phys, Augusta, GA 30904 USA
来源：
SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 11期
关键词：
2-Aminopyrrole; DPEphos; N-arylation; palladium-catalyzed; pyrrolo[2; 3-d]pyrido[1; 2-a]pyrimidine; xantphos; ARYL HALIDES; AMINES;
D O I：
10.1080/00397911.2010.492073
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[image omitted] A versatile class of 2-aminopyrroles containing various electron-withdrawing substituents at the 3-position have been N-arylated on the amine using a palladium-catalyzed cross-coupling reaction. Using this methodology, a pyrimidone-based tricyclic system has been prepared in just one step from a starting 2-aminopyrrole.
引用
收藏
页码：1672 / 1681
页数：10
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