The Fontan circulation: a challenge to William Harvey?

被引：108

作者：

de Leval, MR ^{[1
]}

机构：

[1] Great Ormond St Hosp Sick Children, London WC1N 3JH, England

来源：

NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE | 2005年 / 2卷 / 04期

关键词：

congenital heart disease; Fontan circulation; single ventricle;

D O I：

10.1038/ncpcardio0157

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The Fontan operation, which places the systemic and pulmonary circulations in series and is driven by a single ventricular chamber, is the treatment of choice for patients born with one ventricle. Its introduction 35 years ago was the result of a flurry of experimental and clinical research that had started in the 1940s. A large number of children have benefited and continue to benefit from the Fontan operation, but there is a genuine concern that, despite the refinement of the surgical procedures in the past 20 years, continuing attrition might be inevitable. This adverse effect can lead to a decline in functional capacity, and premature late death.

引用

页码：202 / 208

页数：7

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