Prospective study of high-dose chemotherapy and autologous peripheral stem cell transplantation in adult patients with advanced desmoplastic small round-cell tumour

被引：26

作者：

Bertuzzi, A

Castagna, L

Quagliuolo, V

Ginanni, V

Compasso, S

Magagnoli, M

Balzarotti, M

Nozza, A

Siracusano, L

Timofeeva, I

Sarina, B

Parra, HS

Santoro, A

机构：

[1] Ist Clin Humanitas, Dept Med Oncol & Hematol, I-20089 Milan, Italy

[2] Ist Clin Humanitas, Dept Gen Surg, Milan, Italy

来源：

BRITISH JOURNAL OF CANCER | 2003年 / 89卷 / 07期

关键词：

desmoplastic small round-cell tumour; high-dose chemotherapy;

D O I：

10.1038/sj.bjc.6601304

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A total of 10 desmoplastic small round-cell tumour patients were treated by high-dose chemotherapy with stem cell support. After high-dose chemotherapy, no complete response conversion was obtained and EWS-WT1 fusion transcript detection was positive in the peripheral blood during follow-up in all patients. High-dose chemotherapy did not seem to change the results in desmoplastic small round-cell tumour.

引用

页码：1159 / 1161

页数：3

共 7 条

[1] High-dose chemotherapy in poor-prognosis adult small round-cell tumors: Clinical and molecular results from a prospective study [J].

Bertuzzi, A ;

Castagna, L ;

Nozza, A ;

Quagliuolo, V ;

Siracusano, L ;

Bolzarotti, M ;

Compasso, S ;

Alloisio, M ;

Parra, HS ;

Santoro, A .

JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (08) :2181-2188

[2]

Farhat F, 1996, CANCER, V77, P1363, DOI 10.1002/(SICI)1097-0142(19960401)77:7<1363::AID-CNCR21>3.0.CO

[3]

2-Z

[4] Clinical, pathologic, and molecular spectrum of tumors associated with t(11;22)(p13;q12): Desmoplastic small round-cell tumor and its variants [J].

Gerald, WL ;

Ladanyi, M ;

de Alava, E ;

Cuatrecasas, M ;

Kushner, BH ;

LaQuaglia, MP ;

Rosai, J .

JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (09) :3028-3036

[5] Whole abdominopelvic radiotherapy for desmoplastic small round-cell tumor [J].

Goodman, KA ;

Wolden, SL ;

La Quaglia, MP ;

Kushner, BH .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2002, 54 (01) :170-176

[6] Desmoplastic small round-cell tumor: Prolonged progression-free survival with aggressive multimodality therapy [J].

Kushner, BH ;

LaQuaglia, MP ;

Wollner, N ;

Meyers, PA ;

Lindsley, KL ;

Ghavimi, F ;

Merchant, TE ;

Boulad, F ;

Cheung, NKV ;

Bonilla, MA ;

Crouch, G ;

Kelleher, JF ;

Steinherz, PG ;

Gerald, WL .

JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (05) :1526-1531

[7]

Worley BS, 2001, CANCER RES, V61, P6868

← 1 →