Brain Neuromodulation Techniques: A Review

被引：94

作者：

Lewis, Philip M. ^{[1
,2
,3
]}

Thomson, Richard H. ^{[3
,4
]}

Rosenfeld, Jeffrey V. ^{[1
,2
,3
,5
]}

Fitzgerald, Paul B. ^{[3
,4
]}

机构：

[1] Alfred Hosp, Dept Neurosurg, Melbourne, Vic, Australia

[2] Monash Univ, Dept Surg, Cent Clin Sch, Level 6 Alfred Ctr, Clayton, Vic, Australia

[3] Monash Univ, Monash Inst Med Engn, Clayton, Vic, Australia

[4] Monash Univ, Monash Alfred Psychiat Res Ctr, Cent Clin Sch, Melbourne, Vic, Australia

[5] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Bethesda, MD 20814 USA

来源：

NEUROSCIENTIST | 2016年 / 22卷 / 04期

关键词：

neuromodulation; neuropsychiatry; cognitive; implant; bionics; brain; TRANSCRANIAL MAGNETIC STIMULATION; DORSOLATERAL PREFRONTAL CORTEX; EPIDURAL CORTICAL STIMULATION; CENTRAL-NERVOUS-SYSTEM; HUMAN MOTOR CORTEX; MAJOR DEPRESSION; DOUBLE-BLIND; ELECTRICAL-STIMULATION; ELECTROMAGNETIC-FIELDS; ANIMAL ELECTRICITY;

D O I：

10.1177/1073858416646707

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The modulation of brain function via the application of weak direct current was first observed directly in the early 19th century. In the past 3 decades, transcranial magnetic stimulation and deep brain stimulation have undergone clinical translation, offering alternatives to pharmacological treatment of neurological and neuropsychiatric disorders. Further development of novel neuromodulation techniques employing ultrasound, micro-scale magnetic fields and optogenetics is being propelled by a rapidly improving understanding of the clinical and experimental applications of artificially stimulating or depressing brain activity in human health and disease. With the current rapid growth in neuromodulation technologies and applications, it is timely to review the genesis of the field and the current state of the art in this area.

引用

页码：406 / 421

页数：16

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