Quality Evaluation of the Tugaksheeree Samples by ATR-FTIR Spectroscopy Using Multicomponent Analysis

被引:4
作者
Patel, Nikunj D. [1 ]
Kanaki, Niranjan S. [1 ]
机构
[1] Kadi Sarva Vishwavidyalaya, KB Inst Pharmaceut Educ & Res, Gandhinagar 382023, India
关键词
ATR/FTIR; tugaksheeree; fingerprint; HCA; PCA; chemometric methods; CLASSIFICATION;
D O I
10.2174/2210315510999200408125555
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Background: Numerous Ayurvedic formulations contain tugaksheeree as a key ingredient. Tugaksheeree is the starch gained from the rhizomes of two plants, Curcuma angustifolia Roxb. (Zingiberaceae) and Marantaarundinacea (MA) Linn. (Marantaceae). Objective: The primary concerns in quality assessment of Tugaksheeree occur due to adulteration or substitution. Methods: In the current study, Fourier Transform Infrared (FTIR) technique with Attenuated Total Reflectance (ATR) facility was used to evaluate the tugaksheeree samples. A total of 10 different samples were studied and transmittance mode was kept to record the spectra devoid of the pellets of KBR. Further treatment was given with multi-component tools by considering the fingerprint region of the spectra. Multivariate analysis was performed by various chemometric methods. Result: Multi-component methods, like Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA), were used to discriminate the tugaksheeree samples using Minitab software. Conclusion: This method can be used as a tool to differentiate samples of tugaksheeree from its adulterants and substitutes.
引用
收藏
页码:377 / 382
页数:6
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