Dynamic Hippocampal and Prefrontal Contributions to Memory Processes and Representations Blur the Boundaries of Traditional Cognitive Domains

被引:43
作者
Rubin, Rachael D. [1 ,2 ,3 ]
Schwarb, Hillary [1 ,4 ]
Lucas, Heather D. [1 ]
Dulas, Michael R. [1 ]
Cohen, Neal J. [1 ,2 ,4 ]
机构
[1] Univ Illinois, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA
[2] Univ Illinois, Dept Psychol, Champaign, IL 61820 USA
[3] Carle Fdn Hosp, Carle Neurosci Inst, Urbana, IL 61801 USA
[4] Univ Illinois, Interdisciplinary Hlth Sci Inst, Urbana, IL 61801 USA
关键词
hippocampus; prefrontal cortex; memory; patient studies; brain networks; MEDIAL TEMPORAL-LOBE; LONG-TERM-MEMORY; COMPLEMENTARY-LEARNING-SYSTEMS; VISUAL WORKING-MEMORY; TOP-DOWN MODULATION; DECISION-MAKING; RELATIONAL MEMORY; AMNESIA DISRUPTS; EPISODIC MEMORY; TASK REPRESENTATION;
D O I
10.3390/brainsci7070082
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The hippocampus has long been known to be a critical component of the memory system involved in the formation and use of long-term declarative memory. However, recent findings have revealed that the reach of hippocampal contributions extends to a variety of domains and tasks that require the flexible use of cognitive and social behavior, including domains traditionally linked to prefrontal cortex (PFC), such as decision-making. In addition, the prefrontal cortex (PFC) has gained traction as a necessary part of the memory system. These findings challenge the conventional characterizations of hippocampus and PFC as being circumscribed to traditional cognitive domains. Here, we emphasize that the ability to parsimoniously account for the breadth of hippocampal and PFC contributions to behavior, in terms of memory function and beyond, requires theoretical advances in our understanding of their characteristic processing features and mental representations. Notably, several literatures exist that touch upon this issue, but have remained disjointed because of methodological differences that necessarily limit the scope of inquiry, as well as the somewhat artificial boundaries that have been historically imposed between domains of cognition. In particular, this article focuses on the contribution of relational memory theory as an example of a framework that describes both the representations and processes supported by the hippocampus, and further elucidates the role of the hippocampal-PFC network to a variety of behaviors.
引用
收藏
页数:17
相关论文
共 158 条
[1]   Creativity and the brain: Uncovering the neural signature of conceptual expansion [J].
Abraham, Anna ;
Pieritz, Karoline ;
Thybusch, Kristin ;
Rutter, Barbara ;
Kroeger, Soeren ;
Schweckendiek, Jan ;
Stark, Rudolf ;
Windmann, Sabine ;
Hermann, Christiane .
NEUROPSYCHOLOGIA, 2012, 50 (08) :1906-1917
[2]   Human Lesion Studies in the 21st Century [J].
Adolphs, Ralph .
NEURON, 2016, 90 (06) :1151-1153
[3]   Inhibition and the right inferior frontal cortex [J].
Aron, AR ;
Robbins, TW ;
Poldrack, RA .
TRENDS IN COGNITIVE SCIENCES, 2004, 8 (04) :170-177
[4]   Dissociable controlled retrieval and generalized selection mechanisms in ventrolateral prefrontal cortex [J].
Badre, D ;
Poldrack, RA ;
Paré-Blagoev, EJ ;
Insler, RZ ;
Wagner, AD .
NEURON, 2005, 47 (06) :907-918
[5]   Cognitive control, hierarchy, and the rostro-caudal organization of the frontal lobes [J].
Badre, David .
TRENDS IN COGNITIVE SCIENCES, 2008, 12 (05) :193-200
[6]   Functional magnetic resonance imaging evidence for a hierarchical organization of the prefrontal cortex [J].
Badre, David ;
D'Esposito, Mark .
JOURNAL OF COGNITIVE NEUROSCIENCE, 2007, 19 (12) :2082-2099
[7]   Left ventrolateral prefrontal cortex and the cognitive control of memory [J].
Badre, David ;
Wagner, Anthony D. .
NEUROPSYCHOLOGIA, 2007, 45 (13) :2883-2901
[8]   Frontal Cortex and the Discovery of Abstract Action Rules [J].
Badre, David ;
Kayser, Andrew S. ;
D'Esposito, Mark .
NEURON, 2010, 66 (02) :315-326
[9]   Is the rostro-caudal axis of the frontal lobe hierarchical? [J].
Badre, David ;
D'Esposito, Mark .
NATURE REVIEWS NEUROSCIENCE, 2009, 10 (09) :659-669
[10]  
Baldo JV, 2000, PSYCHOBIOLOGY, V28, P156