Two cases presenting with pubertal delay and diagnosed as celiac disease

被引:13
作者
Abaci, Ayhan [1 ]
Esen, Ihsan [2 ]
Unuvar, Tolga [1 ]
Arslan, Nur [3 ]
Bober, Ece [1 ]
机构
[1] Dokuz Eylul Univ, Fac Med, Dept Pediat Endocrinol, TR-35340 Izmir, Turkey
[2] Dokuz Eylul Univ, Fac Med, Dept Pediat, TR-35340 Izmir, Turkey
[3] Dokuz Eylul Univ, Fac Med, Div Pediat Gastroenterol Hepatol & Nutr, TR-35340 Izmir, Turkey
关键词
celiac disease; delayed puberty; short stature;
D O I
10.1177/0009922808316185
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Pubertal delay may be due to underlying chronic diseases and primary endocrine diseases. Celiac disease, one of the common malabsorption disorders of childhood, may progress silently in some cases, and the cases diagnosed late present with growth failure or disturbance of pubertal development. Currently, due to the changing face of celiac disease, patients are being diagnosed in adolescence with atypical symptoms and findings. This study describes 2 patients aged 13 and 16 years who presented with pubertal delay and who were diagnosed with celiac disease, concluding that routine screening of celiac disease in the differential diagnosis of delayed puberty should be recommended.
引用
收藏
页码:607 / 609
页数:3
相关论文
共 13 条
[1]   The changing face of coeliac disease [J].
Beattie, R. M. .
ARCHIVES OF DISEASE IN CHILDHOOD, 2006, 91 (12) :955-956
[2]   ZINC, COPPER AND SELENIUM IN REPRODUCTION [J].
BEDWAL, RS ;
BAHUGUNA, A .
EXPERIENTIA, 1994, 50 (07) :626-640
[3]   Catch-up growth and endocrine changes in childhood Celiac disease - Endocrine changes during catch-up growths [J].
Boersma, B ;
Houwen, RHJ ;
Blum, WF ;
van Doorn, J ;
Wit, JM .
HORMONE RESEARCH, 2002, 58 :57-65
[4]   Mechanisms of abnormal puberty in coeliac disease [J].
Bona, G ;
Marinello, D ;
Oderda, G .
HORMONE RESEARCH, 2002, 57 :63-65
[5]   Prevalence of Celiac disease in Turkish children [J].
Ertekin, V ;
Selimoglu, MA ;
Kardas, F ;
Aktas, E .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2005, 39 (08) :689-691
[6]   Guideline for the diagnosis and treatment of celiac disease in children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition [J].
Hill, ID ;
Dirks, MH ;
Liptak, GS ;
Colletti, RB ;
Fasano, A ;
Guandalini, S ;
Hoffenberg, EJ ;
Horvath, K ;
Murray, JA ;
Pivor, M ;
Seidman, EG .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2005, 40 (01) :1-19
[7]   A 14-year-old boy with recent slowing of growth and delayed puberty - Celiac disease. [J].
Israel, EJ ;
Levitsky, LL ;
Anupindi, SA ;
Pitman, MB .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (04) :393-403
[8]  
Karaca Zuleyha, 2007, Hormones (Athens), V6, P71
[9]   A longitudinal assessment of hormonal and physical alterations during normal puberty in boys .5. Rising leptin levels may signal the onset of puberty [J].
Mantzoros, CS ;
Flier, JS ;
Rogol, AD .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (04) :1066-1070
[10]   The changing clinical presentation of coeliac disease [J].
Ravikumara, M. ;
Tuthill, D. P. ;
Jenkins, H. R. .
ARCHIVES OF DISEASE IN CHILDHOOD, 2006, 91 (12) :969-971