Azathioprine Hypersensitivity Presenting as Sweet Syndrome in a Child with Ulcerative Colitis

被引:0
作者
Kim, Mi Jin [1 ]
Jang, Kee Taek [2 ]
Choe, Yon Ho [1 ]
机构
[1] Sungkyunkwan Univ, Dept Pediat, Samsung Med Ctr, Sch Med, Seoul 135710, South Korea
[2] Sungkyunkwan Univ, Dept Pathol, Samsung Med Ctr, Sch Med, Seoul 135710, South Korea
关键词
Azathioprine; Children; Hypersensitivity; Sweet syndrome; DERMATOSIS; PATIENT;
D O I
10.1007/s13312-011-0144-4
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Sweet syndrome is a cutaneous lesion characterized by tender, red inflammatory nodules or papules. We describe a pediatric case of Sweet syndrome presenting 10 days after treatment with azathioprine. As azathioprine is widely used in children with inflammatory bowel disease, clinicians should be aware of this unusual adverse reaction.
引用
收藏
页码:969 / 971
页数:3
相关论文
共 10 条
[1]   Azathioprine: current status and future considerations [J].
el-Azhary, RA .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2003, 42 (05) :335-341
[2]   Sweet syndrome as a manifestation of azathioprine hypersensitivity [J].
el-Azhary, Rokea A. ;
Brunner, Kelly L. ;
Gibson, Lawrence E. .
MAYO CLINIC PROCEEDINGS, 2008, 83 (09) :1026-1030
[3]   Acute generalized exanthematous pustulosis associated with azathioprine hypersensitivity [J].
Elston, G. E. ;
Johnston, G. A. ;
Mortimer, N. J. ;
Harman, K. E. .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2007, 32 (01) :52-53
[4]   Azathioprine hypersensitivity reaction in a patient with ulcerative colitis [J].
Garey, KW ;
Streetman, DS ;
Rainish, MC .
ANNALS OF PHARMACOTHERAPY, 1998, 32 (04) :425-428
[5]   ANTIBODIES TO NEUTROPHIL CYTOPLASMIC ANTIGENS - A SEROLOGIC MARKER FOR SWEETS SYNDROME [J].
KEMMETT, D ;
HARRISON, DJ ;
HUNTER, JAA .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1991, 24 (06) :967-969
[6]   Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity [J].
McGovern, DPB ;
Travis, SPL ;
Duley, J ;
Shobowale-Bakre, EM ;
Dalton, HR .
GASTROENTEROLOGY, 2002, 122 (03) :838-839
[7]   Diffuse febrile dermatosis in a patient with active ulcerative colitis under treatment with steroids and azathioprine: a case of Sweet's syndrome - Case report and review of literature [J].
Paoluzi, OA ;
Crispino, P ;
Amantea, A ;
Pica, R ;
Iacopini, F ;
Consolazio, A ;
Di Palma, V ;
Rivera, M ;
Paoluzi, P .
DIGESTIVE AND LIVER DISEASE, 2004, 36 (05) :361-366
[8]  
Sarkany RPE, 1998, BRIT J DERMATOL, V138, P365
[9]  
SU WPD, 1986, CUTIS, V37, P167
[10]   Azathioprine hypersensitivity presenting as a neutrophilic dermatosis in a man with ulcerative colitis [J].
Yiasemides, Eleni ;
Thom, Graham .
AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2009, 50 (01) :48-51