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Univ Laval, Quebec Heart & Lung Inst, Inst Univ Cardiol & Pneumol Quebec, 2725 Chemin St Foy,A-2075, Ste Foy, PQ G1V 4G5, Canada Univ Laval, Quebec Heart & Lung Inst, Inst Univ Cardiol & Pneumol Quebec, 2725 Chemin St Foy,A-2075, Ste Foy, PQ G1V 4G5, Canada