共 11 条
COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?
被引:147
作者:

Revannavar, Shweta Mallikarjun
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机构:
Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India

Supriya, P. S.
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Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India

Samaga, Laxminarayana
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机构:
Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India

Vineeth, V. K.
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Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India
机构:
[1] Nitte Univ, Gen Med, KS Hegde Med Acad, Mangalore, Karnataka, India
关键词:
COVID-19;
diabetes;
tropical medicine (infectious disease);
stroke;
D O I:
10.1136/bcr-2021-241663
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. She incidentally tested positive for COVID-19. CT paranasal sinus and MRI brain revealed left-sided pansinusitis with acute infarct in the left parieto-occipital region without angioinvasion. An emergency functional endoscopic sinus procedure was done, which confirmed mucormycosis on histopathological examination. After 1 week of conventional amphotericin B and antibiotics, repeat CT brain showed improvement in mucosal thickening and sinusitis. This case is a rare presentation of mucormycosis associated with rapid progression to orbital apex syndrome with brain infarction in a patient with non-ketotic diabetes and COVID-19. Early diagnosis and treatment are essential to prevent further end-organ damage. It is also interesting that there was no angioinvasion and transient periarterial inflammation was attributed to brain infarction.
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