Regioselective synthesis of 2-[(E)-(benzo[d]thiazol-2(3H)-ylidene)(cyano)methyl]thiazoles

被引：5
|
作者：
Bakavoli, Mehdi [2 ]
Beyzaei, Hamid [1 ]
Rahimizadeh, Mohammad [2 ]
Eshghi, Hossein [2 ]
机构：
[1] Univ Zabol, Fac Sci, Dept Chem, Zabol 98615538, Iran
[2] Ferdowsi Univ Mashhad, Fac Sci, Dept Chem, Mashhad 917751436, Iran
来源：
HETEROCYCLIC COMMUNICATIONS | 2011年 / 17卷 / 3-4期
关键词：
alpha-bromocarbonyl compounds; benzo[d]thiazole; Hantzsch's synthesis; heterocyclization; phosphorus pentasulfide; regioselective synthesis; thiazole; THIAZOLES; INHIBITORS;
D O I：
10.1515/HC.2011.031
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cyclocondensation of 2-[bis(methylthio)methylene]malononitrile and 2-amino-benzenthiol afforded 2-(benzo[d]thiazol-2-yl) malononitrile. This compound, on treatment with phosphorus pentasulfide, gave the corresponding thioamide derivative in a regioselective manner. Reaction of this compound with several alpha-bromocarbonyl compounds gave new 2-[(E)-(benzo[d]thiazol-2(3H)-ylidene)(cyano)methyl]thiazoles.
引用
收藏
页码：151 / 154
页数：4
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