Safety Nanocosmetics: Triblock Copolymer Nanostructured Lipid Carriers and application on Hair Cosmetics

被引:1
作者
Dini, A. X. P. [1 ]
Costa, A. F. [1 ]
Favaro, W. J. [1 ]
Duran, N. [1 ,2 ]
机构
[1] Univ Estadual Campinas, UNICAMP, Inst Biol,Dept Genet,Evolut & Bioagents, Urogenital Carcinogenesis & Immunotherapy Lab, Campinas, SP, Brazil
[2] Fed Univ ABC UFABC, Nanomed Res Unit Nanomed, Santo Andre, SP, Brazil
来源
7TH NANOSAFE INTERNATIONAL CONFERENCE ON HEALTH AND SAFETY ISSUES RELATED TO NANOMATERIALS FOR A SOCIALLY RESPONSIBLE APPROACH, NANOSAFE 2020 | 2021年 / 1953卷
基金
巴西圣保罗研究基金会;
关键词
IN-VITRO; NANOPARTICLES; STABILITY;
D O I
10.1088/1742-6596/1953/1/012001
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Nanotechnology has been extensively studied for application in the pharmaceutical area. Nanostructured lipid carriers (NLC) are safe lipid nanoparticles that improve the performance of cosmetic products due to their high superficial area. The NLC were produced with the solid lipids, cupuacu and lanolin, and the liquid lipid, buriti. The production method was by high pressure homogenizer, with three cycles at 600 bar. The produced nanoparticles presented diameters around 200 nanometers and a low polydispersity index. The images obtained by electron cryo-transmission electron microscopy (TEM) showed an NLC solution with nanoparticles with circular projection structures with dimensions between 15 nm to 140 nm, without signs of aggregation between these structures. The Scanning Electron Microscopy (SEM) analysis showed visible changes in the capillary structure after treatment with the conditioner containing NLC versus the non-treated wicks. The outer cuticle are seal and have a uniform appearance and brightness to the naked eye after application of conditioner containing NLC. The color seems not to vary when comparing the hair treated with the conditioner base (without NLC) and the control. Otherwise, after the treatment with NLCcontaining conditioner it was observed an improvement on the average parameter. Then, our results indicated a significant improvement in the brightness caused by the nanoparticle action, as well as a contribution to the retention of moisture in the capillaries, reduction of hair wicks frizz and for greater brightness.
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页数:10
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