Amide proton transfer imaging of tumors: theory, clinical applications, pitfalls, and future directions

被引：48

作者：

Kamimura, Kiyohisa ^{[1
]}

Nakajo, Masanori ^{[1
]}

Yoneyama, Tomohide ^{[1
]}

Takumi, Koji ^{[1
]}

Kumagae, Yuichi ^{[1
]}

Fukukura, Yoshihiko ^{[1
]}

Yoshiura, Takashi ^{[1
]}

机构：

[1] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Radiol, 8-35-1 Sakuragaoka, Kagoshima 8908544, Japan

来源：

JAPANESE JOURNAL OF RADIOLOGY | 2019年 / 37卷 / 02期

基金：

日本学术振兴会;

关键词：

Amide proton transfer; Chemical exchange saturation transfer; Tumor; EXCHANGE SATURATION-TRANSFER; HIGH-GRADE GLIOMAS; MAGNETIZATION-TRANSFER ASYMMETRY; APPARENT DIFFUSION-COEFFICIENT; BLOOD-VOLUME MAPS; IN-VIVO; DIAGNOSTIC PERFORMANCE; CONTRAST ENHANCEMENT; RADIATION NECROSIS; ENDOGENOUS PROTEIN;

D O I：

10.1007/s11604-018-0787-3

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Amide proton transfer (APT) imaging is an emerging molecular magnetic resonance imaging technique based on chemical exchange saturation transfer (CEST). APT imaging has shown promise in oncologic imaging, especially in the imaging of brain tumors. This review article illustrates the theory of CEST/APT imaging and describes the clinical utility, pitfalls, and potential for future development of APT imaging.

引用

页码：109 / 116

页数：8

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