Paramyxovirus RNA synthesis, mRNA editing, and genome hexamer phase: A review

被引：52

作者：

Kolakofsky, Daniel ^{[1
]}

机构：

[1] Univ Geneva, Dept Microbiol & Mol Med, Sch Med, Geneva, Switzerland

来源：

VIROLOGY | 2016年 / 498卷

关键词：

Paramyxoviridae family; Bipartite replication promoters; MRNA editing; Genome hexamer phase; VESICULAR STOMATITIS-VIRUS; P-PROTEIN; REPLICATION; POLYMERASE; PROMOTER; RULE; NUCLEOPROTEIN; NUCLEOCAPSIDS; INITIATION; MECHANISM;

D O I：

10.1016/j.virol.2016.08.018

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The recent flurry of high resolution structures of Negative Strand RNA Virus RNA-dependent RNA polymerases has rekindled interest in the manner in which these polymerases, and in particular those of the nonsegmented viruses, recognize the RNA sequences that control mRNA synthesis and genome replication. In the light of these polymerase structures, we re-examine some unusual aspects of the Paramyxoviridae, namely bipartite replication promoters and mRNA editing, and the manner in which these properties are governed by genome hexamer phase. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：94 / 98

页数：5