Bioencapsulation in sol-gel glasses

被引：9

作者：

Bergogne, L ^{[1
]}

Fennouh, S ^{[1
]}

Livage, J ^{[1
]}

Roux, C ^{[1
]}

机构：

[1] Univ Paris 06, F-75252 Paris, France

来源：

ORGANIC/INORGANIC HYBRID MATERIALS | 1998年 / 519卷

关键词：

D O I：

10.1557/PROC-519-171

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Bioencapsulation in sol-gel materials has been widely studied during the past decade. Trapped species appear to retain their bioactivity in the porous silica matrix. Small analytes can diffuse through the pores allowing bioreactions to be performed in-situ, inside the soil-gel glass. A wide range of biomolecules and micro-organisms have been encapsulated. The catalytic activity of enzymes is used for the realization of biosensors or bioreactors. Antibody-antigen recognition has been shown to be feasible within sol-gel matrices. Trapped antibodies bind specifically the corresponding haptens and can be used for the detection of traces of chemicals. Even whole cells are now encapsulated without any alteration of their cellular organization. They can be used for the production of chemicals or as antigens for immunoassays.

引用

页码：171 / 181

页数：11