Dosimetric effects of bolus and lens shielding in treating ocular lymphomas with low-energy electrons

被引:2
作者
Young, Lori [1 ]
Wootton, Landon S. [1 ]
Kalet, Alan M. [1 ]
Gopan, Olga [1 ,2 ]
Yang, Fei [1 ,3 ]
Day, Samuel [1 ]
Banitt, Michael [4 ]
Liao, Jay J. [1 ]
机构
[1] Univ Washington, Dept Radiat Oncol, Seattle, WA 98195 USA
[2] Northwest Med Phys Grp, Lynnwood, WA 33136 USA
[3] Univ Miami, Dept Radiat Oncol, Miami, FL 33136 USA
[4] Univ Washington, Dept Ophthalmol, Seattle, WA 98195 USA
关键词
Lens shielding; Bolus; Dosimetry; Ocular lymphoma; RADIOCHROMIC FILM DOSIMETRY; RADIATION-THERAPY; ADNEXAL LYMPHOMA; EYE LENS; TISSUE; RADIOTHERAPY; CONJUNCTIVAL; PROTOCOL; FIELD;
D O I
10.1016/j.meddos.2018.01.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radiation therapy is an effective treatment for primary orbital lymphomas. Lens shielding with electrons can reduce the risk of high-grade cataracts in patients undergoing treatment for superficial tumors. This work evaluates the dosimetric effects of a suspended eye shield, placement of bolus, and varying electron energies. Film (GafChromic EBT3) dosimetry and relative output factors were measured for 6, 8, and 10 MeV electron energies. A customized 5-cm diameter circle electron orbital cutout was constructed for a 6 x 6-cm applicator with a suspended lens shield (8-mm diameter Cerrobend cylinder, 2.2-cm length). Point doses were measured using a scanning electron diode in a solid water phantom at depths representative of the anterior and posterior lens. Depth dose profiles were compared for 0-mm, 3-mm, and 5-mm bolus thicknesses. At 5 mm (the approximate distance of the anterior lens from the surface of the cornea), the percent depth dose under the suspended lens shield was reduced to 15%, 15%, and 14% for electron energies 6, 8, and 10 MeV, respectively. Applying bolus reduced the benefit of lens shielding by increasing the estimated doses under the block to 27% for 3-mm and 44% for 5-mm bolus for a 6 MeV incident electron beam. This effect is minimized with 8 MeV electron beams where the corresponding values were 15.5% and 18% for 3-mm and 5-mm bolus. Introduction of a 7-mm hole in 5-mm bolus to stabilize eye motion during treatment altered lens doses by about 1%. Careful selection of electron energy and consideration of bolus effects are needed to account for electron scatter under a lens shield. (C) 2018 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:35 / 42
页数:8
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