Asymmetric synthesis of 4,5-disubstituted 3-hydroxy δ-lactones:: Prelactone B and prelactone V

被引：23
|
作者：
Enders, D [1 ]
Haas, M [1 ]
机构：
[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany
来源：
SYNLETT | 2003年 / 14期
关键词：
asymmetric synthesis; prelactone B; hydrazones; hydrogenation; Crabtree's catalyst;
D O I：
10.1055/s-2003-42060
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient asymmetric synthesis of delta-lactones such as prelactone B has been developed. As key steps, the SAMP/RAMP-hydrazone methodology for the synthesis of 2-methylenated 1,3-diols and a homogenous hydrogenation were used.
引用
收藏
页码：2182 / 2184
页数：3
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