Linking primary and metastatic tumour re-initiation

被引：0

作者：

Nabet, Barzin Y. ^{[1
]}

Minn, Andy J. ^{[1
]}

机构：

[1] Univ Penn, Perelman Sch Med, Dept Radiat Oncol, Abramson Family Canc Res Inst, Philadelphia, PA 19104 USA

来源：

NATURE CELL BIOLOGY | 2015年 / 17卷 / 05期

关键词：

BREAST-CANCER; DISSEMINATION; RESOLUTION; GROWTH; CELLS;

D O I：

10.1038/ncb3173

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Whether the cancer cells responsible for the growth of primary tumours are also able to re-initiate tumour growth after seeding to distant organs is unclear. The characterization of breast cancer cells with both of these attributes now identifies the functional and molecular determinants necessary to mediate primary tumour formation and re-initiation at the secondary site.

引用

页码：542 / 543

页数：2

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