Design, synthesis and evaluation of a chiral propranolol selector.

被引：4

作者：

delCampo, C ^{[1
]}

Llama, EF ^{[1
]}

Sinisterra, JV ^{[1
]}

机构：

[1] UNIV COMPLUTENSE MADRID,FAC FARM,DEPT QUIM ORGAN & FARMACEUT,E-28040 MADRID,SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 09期

关键词：

D O I：

10.1016/0957-4166(96)00337-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Synthesis of enantiomerically pure (S)-(-)-propranolol, the most active of the widely used beta-blockers adrenergics, was achieved using a new chiral stationary phase (CSP) for the separation of a derivative. This simple methodology shows a significant improvement in the separation of the enantiomers of a propranolol derivative over previous methods. Copyright (C) 1996 Published by Elsevier Science Ltd

引用

页码：2627 / 2631

页数：5

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