Solubility prediction of solutes in aqueous mixtures of ethylene glycols

被引：11

作者：

Jouyban, A. ^{[1
,2
]}

Soltanpour, Sh. ^{[3
]}

Tamizi, E. ^{[4
]}

机构：

[1] Tabriz Univ Med Sci, Fac Pharm, Tabriz 51664, Iran

[2] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz 51664, Iran

[3] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz 51664, Iran

[4] Tabriz Univ Med Sci, Pharmaceut Nanotechnol Res Ctr, Tabriz 51664, Iran

来源：

PHARMAZIE | 2008年 / 63卷 / 07期

关键词：

D O I：

10.1691/ph.2008.7856

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The applicability of a trained version of the Jouyban-Acree model, for predicting the solubility of solutes in aqueous mixtures of ethylene glycol and its polymerized forms was shown. The solubilities of 8 drugs in binary mixtures were determined and the mean percentage deviation (MPD) was calculated as a prediction accuracy criterion and the overall MPD (+/- SD) was 23.2 (+/- 13.1) %.

引用

页码：548 / 550

页数：3

共 14 条

[1] EXPANDED SOLUBILITY PARAMETER APPROACH .1. NAPHTHALENE AND BENZOIC-ACID IN INDIVIDUAL SOLVENTS [J].