A hunger for hunger: a review of palliative therapies for cancer-associated anorexia

被引:39
作者
Childs, Daniel S. [1 ]
Jatoi, Aminah [2 ]
机构
[1] Mayo Clin, Dept Med, Rochester, MN USA
[2] Mayo Clin, Dept Oncol, Rochester, MN USA
关键词
Loss of appetite; anorexia; appetite stimulants; cancer; nutrition; QUALITY-OF-LIFE; HYDROXY-BETA-METHYLBUTYRATE; DOUBLE-BLIND; MEGESTROL-ACETATE; CONTROLLED-TRIAL; PATIENT SATISFACTION; CACHEXIA; ARGININE; WEIGHT; SUPPLEMENTATION;
D O I
10.21037/apm.2018.05.08
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Cancer-associated anorexia, or loss of appetite, is prevalent, distressing to patients and their families, and associated with poorer outcomes in patients with advanced cancer. A well-defined therapeutic strategy remains to be defined. We present here a review of appetite loss in cancer patients with a summary of how best to manage this symptom.
引用
收藏
页码:50 / 58
页数:9
相关论文
共 56 条
[1]   ESPEN guidelines on nutrition in cancer patients [J].
Arends, Jann ;
Bachmann, Patrick ;
Baracos, Vickie ;
Barthelemy, Nicole ;
Bertz, Hartmut ;
Bozzetti, Federico ;
Fearon, Ken ;
Huetterer, Elisabeth ;
Isenring, Elizabeth ;
Kaasa, Stein ;
Krznaric, Zeljko ;
Laird, Barry ;
Larsson, Maria ;
Laviano, Alessandro ;
Muhlebach, Stefan ;
Muscaritoli, Maurizio ;
Oldervoll, Line ;
Ravasco, Paula ;
Solheim, Tora ;
Strasser, Florian ;
de van der Schueren, Marian ;
Preiser, Jean-Charles .
CLINICAL NUTRITION, 2017, 36 (01) :11-48
[2]   ASPEN Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation [J].
August, David Allen ;
Huhmann, Maureen B. .
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 2009, 33 (05) :472-500
[3]   Simple nutritional intervention in patients with advanced cancers of the gastrointestinal tract, non-small cell lung cancers or mesothelioma and weight loss receiving chemotherapy: a randomised controlled trial [J].
Baldwin, C. ;
Spiro, A. ;
McGough, C. ;
Norman, A. R. ;
Gillbanks, A. ;
Thomas, K. ;
Cunningham, D. ;
O'Brien, M. ;
Andreyev, H. J. N. .
JOURNAL OF HUMAN NUTRITION AND DIETETICS, 2011, 24 (05) :431-440
[4]   Oral Nutritional Interventions in Malnourished Patients With Cancer: A Systematic Review and Meta-Analysis [J].
Baldwin, Christine ;
Spiro, Ayelet ;
Ahern, Roger ;
Emery, Peter W. .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2012, 104 (05) :371-385
[5]  
BARBUL A, 1990, SURGERY, V108, P331
[6]   A randomized, double-blind, placebo-controlled trial of a β-hydroxyl β-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122) [J].
Berk, Lawrence ;
James, Jennifer ;
Schwartz, Anna ;
Hug, Eugen ;
Mahadevan, Anand ;
Samuels, Michael ;
Kachnic, Lisa .
SUPPORTIVE CARE IN CANCER, 2008, 16 (10) :1179-1188
[7]   Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: A double-blind, placebo-controlled study [J].
Bruera, E ;
Strasser, F ;
Palmer, JL ;
Willey, J ;
Calder, K ;
Amyotte, G ;
Baracos, V .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (01) :129-134
[8]   PLASMA AND CSF TRYPTOPHAN IN CANCER ANOREXIA [J].
CANGIANO, C ;
CASCINO, A ;
CECI, F ;
LAVIANO, A ;
MULIERI, M ;
MUSCARITOLI, M ;
ROSSIFANELLI, F .
JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION, 1990, 81 (03) :225-233
[9]   Nutritional treatment for acquired immunodeficiency virus-associated wasting using β-hydroxy β-methylbutyrate, glutamine, and arginine:: A randomized, double-blind, placebo-controlled study [J].
Clark, RH ;
Feleke, G ;
Din, M ;
Yasmin, T ;
Singh, G ;
Khan, FA ;
Rathmacher, JA .
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 2000, 24 (03) :133-139
[10]   ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia [J].
Currow, D. ;
Temel, J. S. ;
Abernethy, A. ;
Milanowski, J. ;
Friend, J. ;
Fearon, K. C. .
ANNALS OF ONCOLOGY, 2017, 28 (08) :1949-1956