Intracellular hyperthermia for cancer using magnetite cationic liposomes

被引：115

作者：

Shinkai, M ^{[1
]}

Yanase, M

Suzuki, M

Honda, H

Wakabayashi, T

Yoshida, J

Kobayashi, T

机构：

[1] Nagoya Univ, Grad Sch Engn, Dept Biotechnol, Chikusa Ku, Nagoya, Aichi 4648603, Japan

[2] Nagoya Univ, Sch Med, Dept Neurosurg, Showa Ku, Nagoya, Aichi 4668550, Japan

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 1999年 / 194卷 / 1-3期

关键词：

magnetite cationic liposomes; magnetite; intracellular hyperthermia; glioma cells; induction heating;

D O I：

10.1016/S0304-8853(98)00586-1

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We have developed 'magnetite cationic liposomes' (MCLs) as a new heating mediator for hyperthermia. The hyperthermic effect on solid glioma tissue grown subcutaneously in F344 rats was investigated. Complete tumor regression was observed in about 90% of the rats by three times of repeated heating. Furthermore, induction of antitumor immunity for T-9 rat glioma using MCLs was investigated. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：176 / 184

页数：9

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