Production of hydroxyapatite-bacterial cellulose nanocomposites from agroindustrial wastes

被引:37
作者
Duarte, Eden B. [1 ]
das Chagas, Bruna S. [1 ]
Andrade, Fabia K. [2 ]
Brigida, Ana I. S. [3 ]
Borges, Maria F. [2 ]
Muniz, Celli R. [2 ]
Souza Filho, Men de Sa M. [2 ]
Morais, Joao P. S. [4 ]
Feitosa, Judith P. A. [1 ]
Rosa, Morsyleide F. [2 ]
机构
[1] Univ Fed Ceara, BR-60455760 Fortaleza, Ceara, Brazil
[2] Embrapa Trop Agroind, BR-60511110 Fortaleza, Ceara, Brazil
[3] Embrapa Food Technol, BR-23020470 Rio De Janeiro, RJ, Brazil
[4] Embrapa Cotton, BR-58428095 Campina Grande, PB, Brazil
关键词
Agave sisalana; Anacardium occidentale; In vitro test; Agribusiness; Nanotechnology; IN-VIVO BIOCOMPATIBILITY; BIOMEDICAL APPLICATIONS; BIOMIMETIC SYNTHESIS; PROTEIN ADSORPTION; BONE SUBSTITUTES; CELLS; CELLULOSE/HYDROXYAPATITE; SCAFFOLDS; BEHAVIOR;
D O I
10.1007/s10570-015-0734-8
中图分类号
TB3 [工程材料学]; TS [轻工业、手工业、生活服务业];
学科分类号
0805 ; 080502 ; 0822 ;
摘要
In the present work, bionanocomposites based on bacterial cellulose (BC) obtained from alternative sources (cashew juice and sisal liquid waste) and hydroxyapatite (HA) were developed. BC-HA composites were prepared through alternate immersion in CaCl2 and Na2HPO4 solutions. Cellulose was successfully produced from the alternative sources of media without the need for additional supplementation and HA crystals that homogeneously precipitated onto the BC surface. The Ca/P ratio ranged from 1.53 to 1.58, indicating the presence of calcium-deficient HA in the composites; this is a phase similar to biological apatite. After immersion into synthetic body fluid, the HA layer formed on the surface of pure BC and the composites, attesting the material's bioactivity. Moreover, apatite deposition on the composites was up to three times higher than observed on pure cellulose with no significant desorption of apatite from the composites. These results support that the BC derived from agroindustrial wastes have potential to produce nanocomposites of cellulose/HA for use in bone tissue regeneration.
引用
收藏
页码:3177 / 3187
页数:11
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