Protein detection with aptamer biosensors

被引：181
作者：
Strehlitz, Beate [1 ]
Nikolaus, Nadia [1 ]
Stoltenburg, Regina [1 ]
机构：
[1] UFZ Helmholtz Ctr Environm Res, UBZ, D-04318 Leipzig, Germany
来源：
SENSORS | 2008年 / 8卷 / 07期
关键词：
aptamer; protein; biosensor; SELEX;
D O I：
10.3390/s8074296
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Aptamers have been developed for different applications. Their use as new biological recognition elements in biosensors promises progress for fast and easy detection of proteins. This new generation of biosensor (aptasensors) will be more stable and well adapted to the conditions of real samples because of the specific properties of aptamers.
引用
收藏
页码：4296 / 4307
页数：12
相关论文
共 35 条
  • [1] Aptasensor development: Elucidation of critical parameters for optimal aptamer performance
    Baldrich, E
    Restrepo, A
    O'Sullivan, CK
    [J]. ANALYTICAL CHEMISTRY, 2004, 76 (23) : 7053 - 7063
  • [2] A novel electrochemical detection method for aptamer biosensors
    Bang, GS
    Cho, S
    Kim, BG
    [J]. BIOSENSORS & BIOELECTRONICS, 2005, 21 (06) : 863 - 870
  • [3] SELECTION OF SINGLE-STRANDED-DNA MOLECULES THAT BIND AND INHIBIT HUMAN THROMBIN
    BOCK, LC
    GRIFFIN, LC
    LATHAM, JA
    VERMAAS, EH
    TOOLE, JJ
    [J]. NATURE, 1992, 355 (6360) : 564 - 566
  • [4] Aptamer-based biosensors for label-free voltammetric detection of lysozyme
    Cheng, Alan K. H.
    Ge, Bixia
    Yu, Hua-Zhong
    [J]. ANALYTICAL CHEMISTRY, 2007, 79 (14) : 5158 - 5164
  • [5] INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS
    ELLINGTON, AD
    SZOSTAK, JW
    [J]. NATURE, 1990, 346 (6287) : 818 - 822
  • [6] Quantum-dot/aptamer-based ultrasensitive multi-analyte electrochemical biosensor
    Hansen, JA
    Wang, J
    Kawde, AN
    Xiang, Y
    Gothelf, KV
    Collins, G
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (07) : 2228 - 2229
  • [7] Novel electrochemical sensor system for protein using the aptamers in sandwich manner
    Ikebukuro, K
    Kiyohara, C
    Sode, K
    [J]. BIOSENSORS & BIOELECTRONICS, 2005, 20 (10) : 2168 - 2172
  • [8] Jayasena SD, 1999, CLIN CHEM, V45, P1628
  • [9] HIGH-RESOLUTION MOLECULAR DISCRIMINATION BY RNA
    JENISON, RD
    GILL, SC
    PARDI, A
    POLISKY, B
    [J]. SCIENCE, 1994, 263 (5152) : 1425 - 1429
  • [10] Kubik MF, 1997, J IMMUNOL, V159, P259
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