High efficiency production of astaxanthin by autotrophic cultivation of Haematococcus pluvialis in a bubble column photobioreactor

被引：42

作者：

Ranjbar, Reza ^{[1
]}

Inoue, Ryota ^{[1
]}

Shiraishi, Hironori ^{[1
]}

Katsuda, Tomohisa ^{[1
]}

Katoh, Shigeo ^{[1
]}

机构：

[1] Kobe Univ, Grad Sch Engn, Kobe, Hyogo 6578501, Japan

来源：

BIOCHEMICAL ENGINEERING JOURNAL | 2008年 / 39卷 / 03期

关键词：

Haematococcus pluvialis; autotrophic culture; bubble column; fed-batch; nitrate concentration; astaxanthin;

D O I：

10.1016/j.bej.2007.11.010

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Haematococcus pluvialis was cultivated under photoautotrophic conditions in a bubble column with fed-batch addition of nutrients, especially nitrate, and a cell number above 5 x 106 cells mL(-1) was attained after 300 h. The reduction of nutrient concentrations accompanied by dilution of the fermentation broth and an increase in the light intensity enhanced accumulation of astaxanthin. The final astaxanthin concentration of 390 mg L-1 was several times higher than ever reported. This combination of fed-batch addition of nutrients and dilution of broth for nutrient deficiency is a promising method for attainment of high cell and astaxanthin concentrations in a bubble column photobioreactor. (c) 2007 Elsevier B.V. All rights reserved.

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收藏

页码：575 / 580

页数：6

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