Discordant findings of different positron emission tomography/CT tracers in a case of glioblastoma

被引：0

作者：

Kumar, Ram Elumalai ^{[1
]}

Gupta, Nitin ^{[1
]}

Ranjan, Rajeev ^{[2
]}

Verma, Ritu ^{[1
]}

Belho, Ethel Shangne ^{[1
]}

Sen, Ishita Barat ^{[3
]}

机构：

[1] Sir Ganga Ram Hosp, Mahajan Imaging Ctr, Dept Nucl Med & PET CT, New Delhi, India

[2] Sir Ganga Ram Hosp, Dept Neurol, New Delhi, India

[3] Fortis Mem Res Inst, Dept Nucl Med & PET CT, Gurugram, Haryana, India

来源：

WORLD JOURNAL OF NUCLEAR MEDICINE | 2021年 / 20卷 / 04期

关键词：

F-18-DOPA; F-18-2-fluoro-2-deoxy-D-glucose; dual tracer positron emission tomography; false-negative positron emission tomography/CT; high-grade glioblastoma; BRAIN; PET;

D O I：

10.4103/wjnm.wjnm_135_20

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

F-18-2-fluoro-2-deoxy-D-glucose ([F-18]-FDG) positron emission tomography (PET) CT has proven useful in the evaluation of high-grade glioma and is also useful as a predictor of the degree of malignancy in newly diagnosed brain tumors. It is commonly accepted that high-grade gliomas are characterized by increased FDG uptake, whereas the low-grade glioma demonstrates reduced or absent FDG uptake. [F-18]-FDOPA is an amino acid PET tracer which is a marker of the proliferative activity of brain tumors and demonstrates positive uptake in all grades of brain tumors; however, the degree of tracer uptake is significantly higher in high-grade tumors as compared to low-grade tumors. Here, we discuss a case where both FDG and DOPA PET/CT scans raised suspicion of low-grade glioma; however, the final histopathology report confirmed WHO grade IV Glioblastoma.

引用

页码：401 / 404

页数：4

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