Survival Analysis of Pathological T3a Upstaging in Clinical T1 Renal Cell Carcinoma

被引：5

作者：

Lai, Gu-Shun ^{[1
]}

Li, Jian-Ri ^{[2
,3
,4
]}

Wang, Shian-Shiang ^{[2
,3
,5
]}

Chen, Chuan-Shu ^{[2
,3
]}

Yang, Chun-Kuang ^{[2
]}

Hung, Sheng-Chun ^{[2
,3
]}

Cheng, Chen-Li ^{[2
,3
]}

Ou, Yen-Chuan ^{[3
,6
]}

Chiu, Kun-Yuan ^{[2
,5
]}

机构：

[1] Taichung Vet Gen Hosp, Chiayi Branch, Dept Surg, Div Urol, Chiayi, Taiwan

[2] Taichung Vet Gen Hosp, Dept Surg, Div Urol, Taichung, Taiwan

[3] Chung Shan Med Univ, Inst Med, Taichung, Taiwan

[4] Hungkuang Univ, Dept Med & Nursing, Taichung, Taiwan

[5] Natl Chi Nan Univ, Dept Appl Chem, Nantou, Taiwan

[6] Tungs Taichung MetroHarbor Hosp, Dept Urol, Taichung, Taiwan

来源：

IN VIVO | 2020年 / 34卷 / 02期

关键词：

Pathological T3a upstaging; renal cell carcinoma; survival; POSITIVE SURGICAL MARGINS; PARTIAL NEPHRECTOMY; RECURRENCE; MASSES; GUIDELINES; PREDICTORS; SURGERY; IMPACT;

D O I：

10.21873/invivo.11841

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Aim: To evaluate the oncological outcomes of pathological T3a upstaging from clinical T1 renal cell carcinoma. Patients and Methods: We retrospectively studied patients who underwent radical or partial nephrectomy for clinical T1 renal tumors. Results: The median follow-up period was 44 months. At three and five years, the respective overall survival rate was 88.7% and 82.4% in pT3a disease, 95.7% and 93.4% in pT1 (p=0.008), the cancer-specific survival rate, 93.9% and 90.8% in pT3a, 99% and 97.7% in pT1 (p=0.001), and the recurrence-free survival rate, 79.7% and 71.0% in pT3a, and 95.5 and 94.3% in pT1 (p<0.001). Conclusion: Patients with pathological T3a upstaging tumors were associated with a significantly decreased survival rate, along with a higher recurrence rate when compared to those with pathological T1 disease.

引用

页码：799 / 805

页数：7

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