Improved Signal-to-Noise Ratio in Laboratory-Based Phase Contrast Tomography

被引:23
作者
Boone, Matthieu N. [1 ]
De Witte, Yoni [1 ]
Dierick, Manuel [1 ]
Almeida, Ana [2 ]
Van Hoorebeke, Luc [1 ]
机构
[1] Univ Ghent, Dept Phys & Astron, B-9000 Ghent, Belgium
[2] Univ Ghent, Dept Pharmaceut, B-9000 Ghent, Belgium
关键词
phase contrast; Bronnikov; mu CT; X-ray refraction; image analysis; pharmaceutics; X-RAY MICROTOMOGRAPHY; COMPUTED-TOMOGRAPHY; MELT EXTRUSION; RESOLUTION; MICROSCOPY; SOFTWARE; NANOTOMOGRAPHY; INTERFEROMETER; RETRIEVAL; IMAGE;
D O I
10.1017/S1431927611012529
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
In conventional X-ray microtomography (mu CT), the three-dimensional (3D) distribution of the attenuation coefficient of X-rays is measured and reconstructed in a 3D volume. As spatial resolution increases, the refraction of X-rays becomes a significant phenomenon in the imaging process. Although this so-called phase contrast was initially a cumbersome feature in lab-based mu CT, special phase retrieval algorithms were developed to exploit these effects. Clear advantages in terms of visualization and analysis can be seen when phase retrieval algorithms are applied, including an increased signal-to-noise ratio. In this work, this is demonstrated both on simulated and measured data.
引用
收藏
页码:399 / 405
页数:7
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