PET/CT in Lymphoma: Current Overview and Future Directions

被引:67
作者
Cheson, Bruce D. [1 ]
机构
[1] Georgetown Univ Hosp, 3800 Reservoir Rd NW, Washington, DC 20007 USA
关键词
POSITRON-EMISSION-TOMOGRAPHY; B-CELL LYMPHOMA; STAGE HODGKINS LYMPHOMA; FONDAZIONE ITALIANA LINFOMI; RESPONSE CRITERIA; FDG-PET; INTERIM-PET; INTERNATIONAL WORKSHOP; LUGANO CLASSIFICATION; FOLLICULAR LYMPHOMA;
D O I
10.1053/j.semnuclmed.2017.09.007
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Over the past several decades, PET has emerged as critical to accurate staging and restaging of lymphomas. Nonetheless, a number of critical issues regarding its optimal use remain. Whereas risk-adapted strategies appear to improve the outcome of patients with Hodgkin lymphoma, results are less convincing in non-Hodgkin lymphoma. Assessment of metabolic tumor volume before treatment may permit novel induction strategies. New drugs that may induce an immune response may result in a false-positive FDG/PET scan, mandating modifications of current criteria to consider tumor flare reactions. Application of PET may be improved by integration of biomarker studies and a better understanding of the role of the microenvironment. Methods to improve the integration of FDG/PET enhance its role in the management of patients with lymphoma, leading to improved patient outcome. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:76 / 81
页数:6
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