The value of growth hormone supplements in ART for poor ovarian responders

被引：57
作者：
de Ziegler, Dominique [1 ]
Streuli, Isabelle [1 ,2 ]
Meldrum, David R. [3 ,4 ]
Chapron, Charles [1 ,2 ]
机构：
[1] Univ Paris 05, AP HP, CHU Cochin, Dept Obstet Gynecol & Reprod Med, Paris, France
[2] CNRS, Cochin Inst, UMR 8104, ISERM,U1016, Paris, France
[3] Univ Calif Los Angeles, Med Ctr, Los Angeles, CA 90024 USA
[4] Reprod Partners Med Grp Redondo Beach Calif, Los Angeles, CA USA
来源：
FERTILITY AND STERILITY | 2011年 / 96卷 / 05期
关键词：
Growth hormone; assisted reproductive technologies; ART; poor response; controlled ovarian stimulation; COS; ovarian failure; aging; IN-VITRO FERTILIZATION; ASSISTED REPRODUCTIVE TECHNOLOGY; STRUCTURE ASSAY PARAMETERS; FACTOR BINDING PROTEIN-1; LIVE BIRTH-RATES; DOUBLE-BLIND; PREGNANCY RATES; GONADOTROPIN STIMULATION; INVITRO FERTILIZATION; OVULATION INDUCTION;
D O I：
10.1016/j.fertnstert.2011.09.049
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Recently, three meta-analyses have concluded that cotreatment with GH improves assisted reproduction outcome in poor controlled ovarian stimulation responders. Although generally GH supplements did not increase controlled ovarian stimulation response or number of oocytes, the supplements improved pregnancy and live-birth rates-thus speaking for an effect on oocyte quality. (Fertil Steril (R) 2011;96:1069-76. (C) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码：1069 / 1076
页数：8
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