Kenyan HIV Clinics With Youth-Friendly Services and Trained Providers Have a Higher Prevalence of Viral Suppression Among Adolescents and Young Adults: Results From an Observational Study

被引:7
作者
Wilson, Kate [1 ]
Onyango, Alvin [2 ]
Mugo, Cyrus [1 ]
Guthrie, Brandon [1 ,3 ]
Slyker, Jennifer [1 ]
Richardson, Barbra [1 ,4 ]
John-Stewart, Grace [1 ,3 ,5 ,6 ]
Inwani, Irene [7 ]
Bukusi, David [8 ]
Wamalwa, Dalton [9 ]
Kohler, Pamela [1 ,10 ]
机构
[1] Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA
[2] Univ Nairobi, Dept Pediat & Child Hlth, Nairobi, Kenya
[3] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
[4] Univ Washington, Dept Biostat, Seattle, WA 98195 USA
[5] Univ Washington, Dept Med, Seattle, WA 98195 USA
[6] Univ Washington, Dept Pediat, Seattle, WA 98195 USA
[7] Kenyatta Natl Hosp, Nairobi, Kenya
[8] Kenyatta Natl Hosp, VCT & HIV Prevent Unit, Nairobi, Kenya
[9] Univ Nairobi, Dept Paediat, Nairobi, Kenya
[10] Univ Washington, Sch Nursing, Dept Child Family & Populat Hlth, Seattle, WA 98195 USA
来源
JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE | 2022年 / 33卷 / 01期
基金
美国国家卫生研究院;
关键词
adolescent and young adults; HIV; HIV care; HIV viral suppression; Kenya; observational study; ANTIRETROVIRAL THERAPY; CHILDREN; RISK;
D O I
10.1097/JNC.0000000000000302
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Sustained viral suppression in adolescents and young adults living with HIV (AYALWH) is necessary for epidemic control. We evaluated facility and individual correlates of viral suppression using programmatic data from AYALWH between ages 10 and 24 years at 24 HIV clinics in Kenya. Binomial regression was used to evaluate correlates of viral load (VL) suppression (<1,000 copies/ml). Of 5,316 AYALWH on antiretroviral therapy >= 6 months, 2,081 (39%) had VLs available in the medical record, of which 76% were virally suppressed. In multivariable analyses, antiretroviral therapy initiation among AYALWH older than 10 years was associated with higher viral suppression than initiation younger than 10 years (adjusted risk ratio [aRR] 10-14 = 1.03, 95% confidence interval [CI] 0.97-1.10; aRR 15-19 = 1.30, 95% CI 1.19-1.41; aRR 20-24 = 1.43, 95% CI 1.24-1.63). Facilities with both youth-friendly services (YFS) and trained providers had significantly higher VL suppression compared with facilities without YFS or trained providers (adjusted odds ratio: 2.07, 95% CI: 1.71-2.52). Viral suppression remains suboptimal among AYALWH. YFS and trained providers plus greater use of VL data may help increase viral suppression among AYALWH.
引用
收藏
页码:45 / 53
页数:9
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