Time-resolved dynamic nuclear polarization enhanced NMR spectroscopy

被引：99
作者：
Bowen, Sean [1 ]
Hilty, Christian [1 ]
机构：
[1] Texas A&M Univ, Dept Chem, College Stn, TX 77843 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 28期
关键词：
enzyme catalysis; hyperpolarization; kinetics; NMR spectroscopy;
D O I：
10.1002/anie.200801492
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Presented) The sensitive touch: Sensitivity constraints in NMR spectroscopy typically call for long measurement times. Hyperpolarization can enhance the time resolution of NMR spectroscopy by removing the need for signal averaging. Reactions such as enzyme catalysis can be followed in real time by hyperpolarized NMR spectroscopy through reduction in the intensity of the substrate resonance as well as the appearance of product resonances (see picture). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：5235 / 5237
页数：3
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