Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy

被引：301

作者：

Jacquemin, E ^{[1
]}

Cresteil, D

Manouvrier, S

Boute, O

Hadchouel, M

机构：

[1] Jeanne de Flandre Hosp, Dept Pediat, F-59037 Lille, France

[2] Hop Bicetre, INSERM, U347, Le Kremlin Bicetre, France

[3] Hop Bicetre, Dept Pediat, Hepatol Unit, Le Kremlin Bicetre, France

来源：

LANCET | 1999年 / 353卷 / 9148期

关键词：

D O I：

10.1016/S0140-6736(05)77221-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：210 / 211

页数：2

共 5 条

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Bosma, PJ ;

Aten, J ;

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Burdelski, M ;

Bernard, O ;

Elferink, RPJO ;

Hadchouel, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (01) :282-287

[2]

Jacquemin E, 1998, HEPATOLOGY, V28, p316A

[3] Recurrent familial prolonged intrahepatic cholestasis of pregnancy associated with chronic liver disease [J].

Leevy, CB ;

Koneru, B ;

Klein, KM .

GASTROENTEROLOGY, 1997, 113 (03) :966-972

[4]

Meng LJ, 1997, HEPATOLOGY, V26, P1573

[5] Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice [J].

Smith, AJ ;

de Vree, JML ;

Ottenhoff, R ;

Elferink, RPJO ;

Schinkel, AH ;

Borst, P .

HEPATOLOGY, 1998, 28 (02) :530-536

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