Palladium-Catalyzed β-Selective Direct Arylation of Porphyrins

被引：37

作者：

Kawamata, Yu ^{[1
]}

Tokuji, Sumito ^{[1
]}

Yorimitsu, Hideki ^{[1
]}

Osuka, Atsuhiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 38期

关键词：

arylation; C-H activation; palladium; porphyrinoids; H BOND ARYLATION; MULTIPLE ARYLATION; METAL; FUNCTIONALIZATION; MECHANISM; REAGENTS;

D O I：

10.1002/anie.201102318

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Four birds with one stone: A palladium catalyst/potassium carbonate/pivalic acid system enables direct arylation of porphyrins by aryl bromides (see scheme; Ar=3,5-tBu2C6H3). The C-H arylation shows excellent β selectivity and does not require porphyrin prefunctionalization, hence representing an extremely efficient method for rapidly providing a series of new β-arylated porphyrins. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8867 / 8870

页数：4