Novel drugs from marine microorganisms

被引：80

作者：

Javed, Faraza ^{[1
]}

Qadir, M. Imran ^{[1
]}

Janbaz, Khalid Hussain ^{[2
]}

Ali, Muhammad ^{[3
]}

机构：

[1] Govt Coll Univ, Coll Pharm, Faisalabad, Pakistan

[2] Bahauddin Zakariya Univ, Dept Pharm, Multan, Pakistan

[3] Bahauddin Zakariya Univ, Inst Biotechnol, Multan, Pakistan

来源：

CRITICAL REVIEWS IN MICROBIOLOGY | 2011年 / 37卷 / 03期

关键词：

Marine microorganisms; Bioactives; Aquatic foodstuff; Biofilms; NATURAL-PRODUCTS; GENE-CLUSTER; LIPID RAFTS; DINOFLAGELLATE; BIOSYNTHESIS; HIV; CHOLESTEROL; INSIGHTS; CELLS; DNA;

D O I：

10.3109/1040841X.2011.576234

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Marine microorganisms have expected mounting consideration on the basis of bioactive metabolites and propose an exclusive prospect to both enhance the amount of aquatic natural foodstuffs in clinical trials as well as speed up their progress. This review focuses particularly on those molecules, originated from marine microorganisms, presently in the medical pipeline that have been recognized or highly expected to be identified based on growing incidental evidence. Particularly karlotoxin class compounds, isolated from dinoflagellate Karlodinium veneficum, offer chances to create new molecules for control of cancer and high serum cholesterol levels.

引用

页码：245 / 249

页数：5

共 46 条

[1] The role of cholesterol and sphingolipids in chemokine receptor function and HIV-I envelope glycoprotein-mediated fusion [J].