Antisense modulation of Toll-like receptor 4 expression

被引：0
|
作者：
不详
机构：
来源：
EXPERT OPINION ON THERAPEUTIC PATENTS | 2003年 / 13卷 / 12期
关键词：
antisense to Toll-like receptor 4; autoimmune diseases; inflammation; sepsis; Toll-like receptor;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A strategy to decrease the expression of Toll-like receptor 4 (TLR4) using antisense oligonucleotides is claimed. TLR4 has been implicated in sepsis syndrome and in chronic inflammatory diseases such as inflammatory bowel disease. Limiting TLR4 expression by the strategy described in the claim may therefore have clinical utility in these diseases.
引用
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页码：1887 / 1889
页数：3
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