Male breast involvement in chronic lymphocytic leukemia. A case report and review of the literature

被引:1
作者
Anagnostopoulou, Vasiliki [1 ]
Mantha, Niki [1 ]
Sapalidis, Konstantinos [2 ]
Tolparidou, Eirini [3 ]
Georgiou, Elisavet [4 ]
Koletsa, Triantafyllia [1 ]
机构
[1] Aristotle Univ Thessaloniki, Dept Pathol, Fac Med, Univ Campus, Thessaloniki 54124, Greece
[2] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Dept Surg 3, Thessaloniki, Greece
[3] Mamatseio Gen Hosp, Lab Pathol, Kozani, Greece
[4] Aristotle Univ Thessaloniki, Fac Med, Dept Biol Chem, Thessaloniki, Greece
关键词
breast lymphoma; male breast; CLL; NHL; plasmacytoid differentiation of CLL; NON-HODGKINS-LYMPHOMA; MALIGNANT-LYMPHOMA; CELL LYMPHOMA; GYNECOMASTIA; PATIENT;
D O I
10.47162/RJME.61.1.27
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Male breast lymphoma is a rare extranodal lymphoma occupying the mammary gland, and it could be either primary or secondary. A 78-year -old man presented an enlargement of the right breast. He had no medical history of interest. On physical examination, a unilateral, painless breast lump was found, with no skin changes or nipple discharge. There was no palpable lymphadenopathy. Routine laboratory tests revealed leukocytosis and lymphocytosis. Excisional biopsy of the breast lesion revealed mammary tissue infiltration by chronic lymphocytic leukemia (CLL) with plasmacytoid features and immunoglobulin G/kappa monotypic expression. To our knowledge, this is the first report of male breast involvement by CLL. Considering important the collection of clinicopathological data of all reported male breast lymphoma cases, a literature review is presented.
引用
收藏
页码:241 / 245
页数:5
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