Solvent-free synthesis of 4,4-bis-functionalized-1,6-dienes and 1,6-diynes on the surface of neutral alumina

被引：24

作者：

Bhar, S ^{[1
]}

Chaudhuri, SK ^{[1
]}

Sahu, SG ^{[1
]}

Panja, C ^{[1
]}

机构：

[1] Jadavpur Univ, Fac Sci, Dept Chem, Organ Chem Sect, Kolkata 700032, W Bengal, India

来源：

TETRAHEDRON | 2001年 / 57卷 / 43期

关键词：

regiocontrol; solid-phase synthesis; supported reagents; dienes and diynes;

D O I：

10.1016/S0040-4020(01)00896-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved procedure has been developed for the synthesis of structurally varied 4,4-bis-functionalized-1,6-dienes and 1,6-diynes through regioselective alkylation of active methylene compounds with several unsymmetrical allyl bromides and propargyl bromide on the surface of neutral alumina impregnated with sodium ethoxide or potassium tert-butoxide in the absence of any solvent under environmentally benign conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：9011 / 9016

页数：6

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